Ksenia Matlawska has received an American Cancer Society Research Scholar Grant to uncover biological mechanisms and therapeutic vulnerabilities driving T-ALL infiltration into the CNS.
Congratulations to Bruno from Ghent University and our own Nitesh on sharing first authorship. This team effort is dedicated to the memory of Pieter, whose scientific curiosity continues to inspire us. https://haematologica.org/article/view/13089
Our fresh and still-steaming Journal of Clinical Investigation preprint is out! 🚀 We explore how T-cell acute lymphoblastic leukemia (T-ALL) exploits inflammatory CXCR3–CXCL10 signaling within the meninges to drive CNS infiltration . Tremendous credit to first author Nitesh Sharma for his dedication and hard work, and to our funders and all our amazing collaborators who made this possible! Link to the paper: JCI - T-cell acute lymphoblastic leukemia exploits a neural proi
Link to the paper: Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia - ScienceDirect